https://nova.newcastle.edu.au/vital/access/ /manager/Index en-au 5 https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:27387 14.3 years. After adjusting for confounders, diabetic subjects were 49% (cause-specific hazard ratio (_cHR) = 1.49, 95% CI: 1.37, 1.62) more likely to develop kidney failure than non-diabetic subjects. Albuminuria categories A3 and A2 were, respectively, 3.40 (95% CI: 3.07, 3.76) and 1.71 (95% CI: 1.53, 1.92) higher risk of kidney failure when compared to A1. For each albumin category, death rate increased as albuminuria increased particularly in diabetic subjects, which was approximately 2 times higher in A3 compared to A1. Considering GFR category, it gradually increased from G1 to G4 and sharply increased from G4 to G5 in both non-diabetic and diabetic subjects. This study has quantified CKD progression in an Asian population within ordinary practice. Diabetic subjects progress through GFR and albuminuria categories and reach kidney failure about twice as rapidly as non-diabetic subjects.]]> Wed 11 Apr 2018 10:07:38 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:7611 60 years. The prevalence was about double using the Cockcroft-Gault equations, i.e. 7.5% (95% CI: 6.9 – 8.2%) and 34.9 (95% CI: 25.9 – 44.8%) in age ≤ 50 and > 50 years, respectively. The prevalence was similar in Caucasians and Asians aged ≤ 60, i.e. 9.9 versus 9.3%. The prevalence was also higher in the diabetic population than in the general population, i.e. 18.2% versus 10.6%. The pooled prevalence of CKD in the general population varied according to age groups. The prevalence is similar in Caucasians and Asians within age 60 years or younger but other age groups need more studies in order to pool. Individual patient meta-analysis would be appropriate to resolve the causes of heterogeneity.]]> Sat 24 Mar 2018 08:34:41 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:12692 Sat 24 Mar 2018 08:16:53 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:46402 2. Results: A total of 53 synchronous urine and serum creatinine samples were analysed. The Nanra equation had a bias of -13.4 ml/min/1.73 m² while the CKD-EPI equation had bias of 14.2 ml/min/1.73 m². Both equations showed a high degree of proportional error and had poor agreement with 24 h urine creatinine clearance. Conclusions: None of the equations were shown to reliably measure the estimated glomerular filtration rate in pregnant women. A valid serum creatinine-based estimated glomerular filtration rate equation in pregnancy is yet to be established.]]> Mon 21 Nov 2022 15:15:45 AEDT ]]>